Imidazo[1,2-a]pyridine, 8-azido-
Imidazo[1,2-a]pyridine, 8-azido-
CAS: 421595-82-6
Molecular Formula: C7H5N5
Imidazo[1,2-a]pyridine, 8-azido- - Names and Identifiers
| Name | Imidazo[1,2-a]pyridine, 8-azido- |
| Synonyms | IMidazo[1,2-a]pyridine, 8-azido- Imidazo[1,2-a]pyridine, 8-azido- |
| CAS | 421595-82-6 |
Imidazo[1,2-a]pyridine, 8-azido- - Physico-chemical Properties
| Molecular Formula | C7H5N5 |
| Molar Mass | 159.1481 |
Imidazo[1,2-a]pyridine, 8-azido- - Introduction
Imidazo[1,2-a]pyridine, 8-azido-is an organic compound with the chemical formula C7H4N6. It is a pyridine compound with an azide group.
The following are the properties of Imidazo[1,2-a]pyridine, 8-azido:
-Appearance: White to light yellow crystalline powder
-Melting point: about 140°C
-Solubility: Soluble in most organic solvents such as dichloromethane, chloroform and methanol
This compound is commonly used in some reactions in organic synthesis, such as click chemistry, olefin cyclization and heterocyclic synthesis. In chemical research and drug development, Imidazo[1,2-a]pyridine, 8-azido-can be used as intermediates or reagents.
The method for preparing Imidazo[1,2-a]pyridine, 8-azido-usually involves a condensation reaction between imidazole-4-carboxylic acid or imidazole-4-carbaldehyde and nitroso acetone, and then through reduction and azidation Reaction to obtain the final product.
Regarding safety information, Imidazo[1,2-a]pyridine, 8-azido-is a potentially explosive compound with a high risk of explosion. Use should follow strict operating procedures and safety measures, and ensure that it is carried out in a safe environment. Avoid contact with combustibles and strong oxidants, and keep away from open flames and high temperatures. At the same time, for the storage and handling of this compound, it is necessary to follow relevant safety operations and regulations to ensure the safety of personnel and the environment. Wear appropriate personal protective equipment such as goggles, gloves and lab coats when using or handling. The waste is preferably disposed of by burning to ensure safe disposal of the compound and elimination of the waste. Always consult and follow the correct safety data sheet before performing any operation.
The following are the properties of Imidazo[1,2-a]pyridine, 8-azido:
-Appearance: White to light yellow crystalline powder
-Melting point: about 140°C
-Solubility: Soluble in most organic solvents such as dichloromethane, chloroform and methanol
This compound is commonly used in some reactions in organic synthesis, such as click chemistry, olefin cyclization and heterocyclic synthesis. In chemical research and drug development, Imidazo[1,2-a]pyridine, 8-azido-can be used as intermediates or reagents.
The method for preparing Imidazo[1,2-a]pyridine, 8-azido-usually involves a condensation reaction between imidazole-4-carboxylic acid or imidazole-4-carbaldehyde and nitroso acetone, and then through reduction and azidation Reaction to obtain the final product.
Regarding safety information, Imidazo[1,2-a]pyridine, 8-azido-is a potentially explosive compound with a high risk of explosion. Use should follow strict operating procedures and safety measures, and ensure that it is carried out in a safe environment. Avoid contact with combustibles and strong oxidants, and keep away from open flames and high temperatures. At the same time, for the storage and handling of this compound, it is necessary to follow relevant safety operations and regulations to ensure the safety of personnel and the environment. Wear appropriate personal protective equipment such as goggles, gloves and lab coats when using or handling. The waste is preferably disposed of by burning to ensure safe disposal of the compound and elimination of the waste. Always consult and follow the correct safety data sheet before performing any operation.
Last Update：2024-04-09 21:32:42
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